- Ab00636-10.0 Anti-Tenascin C [H7]
- Human IgG1
- In Stock
- Ab00636-10.6 Anti-Tenascin C [H7]
- Human Fab fragment
- Ships in 4-5 weeks
- Ab00636-23.0 Anti-Tenascin C [H7]
- Rabbit IgG
- In Stock
Recombinant monoclonal antibody to Tenascin C. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody H7.
UniProt Accession Number of Target Protein: P24821
Alternative Name(s) of Target: TNC; TN-C,
Immunogen: 2D-PAGE gel isolated human Tenascin C from lysate of human melanoma COLO-38 cells.
Specificity: This antibody bind to human Tenascin C.
Application Notes: Tenascin C interacts with a wide range of proteins, in particular integrins and fibronectins. These interactions modify cell adhesion and influence cell migration as well as metalloproteinase expression.
Antibody first published in:
Pini et al. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J Biol Chem. 1998 Aug 21;273(34):21769-76. PMID:9705314
Note on publication: Describes generation, using phage display, of antibodies with subnanomolar affinity against markers of angiogenesis.