United Kingdom (UK)
Recombinant monoclonal antibody to TNFSF13. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma A3D8.
UniProt Accession Number of Target Protein: Q9D777
Alternative Name(s) of Target: Tumor necrosis factor ligand superfamily member 13; CD256; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1
Immunogen: This antibody was raised by immunising Armenian hamsters with maltose binding protein (MBP) fusion of mouse soluble APRIL.
Specificity: This antibody recognises TNFSF13 which is a cytokine which play a role in the regulation of the tumor growth.
Application Notes: A3D8 can be used for the detection of TNFSF13. For instance, it was utilised for the immunofluorescent identification of TNFSF13 (Wang et al., 2014). Finally, another group used this antibody investigate the presence of TNFSF13 via flow cytometry (
Antibody first published in:
Wang et al. Long-term B cell depletion in murine lupus eliminates autoantibody-secreting cells and is associated with alterations in the kidney plasma cell niche. J Immunol. 2014 Apr 1;192(7):3011-20. doi: 10.4049/jimmunol.1302003. Epub 2014 Feb 26. PMID:24574498
Note on publication:
This article describes the use of A3D8 in immunofluorescence analysis.