Antibodies against proteins involved in co-stimulation and other aspects of immune cell regulation are of particular interest to therapeutics developers. Some have already entered the clinic, with more in the development pipeline. However, many aspects of immune cell signalling are still unknown, and researchers require ever more advanced tools to tap into this potential. Absolute Antibody has developed a collection of recombinant engineered antibodies against clinically relevant proteins, including mouse homologues of current therapeutic targets.
- Your favourite research tools, now updated through antibody engineering for improved performance in vivo
- Reduce immunogenicity by matching antibody species to your host organism
- Tailor effector function by choosing from our range of antibody isotypes and subtypes
- Explore new possibilities by combining two of these antibodies into a custom bispecific reagent
Contact us if you have any questions or would like a quote.
See also: Our Fc-Fusion proteins are matched to our collection of immunotherapy antibodies, with all products available in a range of species specific and engineered Fc domains.
Engineered Mouse-Anti-Mouse Antibodies
|Catalog ID||Mouse Target||Antibody Clone||Original Antibody Format|
|Ab01052||4-1BB (CD137)||LOB12.3||Rat IgG1|
|Ab01054||4-1BBL (CD137L)||AT113-2||Rat IgG1|
|Ab00881||4-1BBL (CD137L)||TKS-1||Rat IgG2a|
|Ab01087||CD40L (CD154)||MR1||Hamster IgG|
|Ab00816||CD70||TAN 1-7||Rat IgG2a|
|Ab01028||CD80 (B7-1)||RM80||Rat IgG2a|
|Ab01029||CD86 (B7-2)||PO.3||Rat IgG2b|
|Ab00374||GITR||YGITR 860.103.5||Rat IgG2b|
|Ab00372||LAG3||YLAG 77.5.1||Rat IgG2b|
|Ab00110||OX40 (CD134)||OX86||Rat IgG1|
|Ab01017||PD-1H (VISTA)||mam82||Mouse IgG1|
|Ab01016||PD-1H (VISTA)||MH5A||Hamster IgG|
|Ab00373||PD-L1||YDC 127.1.1||Rat IgG2a|