Anti-DI/DII domain of Dengue E protein [DV78]

Description:

Recombinant monoclonal antibody to DI/DII domain of Dengue E protein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the EBV transformed human B cell clone DV78.

Made with Antibody Sequences licensed from Humabs Biomed SA.

Clone Name:

DV78

Published Application(s):

NTRL, ELISA

Published Species Reactivity:

Dengue Virus

Products based on this clone:

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Ab00244-10.0 Anti-DI/DII domain of Dengue E protein [DV78]
Dengue Virus
Human IgG1
Purified
In Stock

Ab00244-23.0 Anti-DI/DII domain of Dengue E protein [DV78]
Dengue Virus
Rabbit IgG
Purified
In Stock

Alternative Name(s) of Target: Envelope protein
Immunogen: Made by immortalizing IgG-expressing B cells Dengue Virus (DENV) patients after primary or secondary infection.

Specificity: This antibody specifically recognizes an epitope in the DI/DII domain of E protein of DENV-1,DENV-2, DENV-3 and DENV-4 serotypes. This antibody was isolated as a human IgG1 from a patient recovered from a primary DENV-3 infection and neutralises infection.

Antibody first published in: Beltramello et al. The human immune response to Dengue Virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe. 2010 Sep 16;8(3):271-83. PMID:20833378

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