Immunoglobulin Fc domains (Ig Fc domains)

Figure 1. A schematic representation of the structure of four immunoglobulin (Ig) classes or isotypes and their Fc domains. The Ig Fc domain does not bind antigen- see Antibody Isotypes and Subtypes and Antibody Effector Functions for a detailed account on structure and function of antibodies.

We offer a range of isotype- and species-specific Ig Fc domains – please see the table below.

Recombinant Ig Fc domains are recommended as:

• Assay standards or controls (see IgG Fc Fusion Proteins)
• Immunogens to generate antibodies against the immunoglobulin Fc domains and other Ig Fc domain applications

For further information or to request a species or isotype not yet shown, please contact us.