Fc fusion proteins (also known as Fc chimeric fusion proteins, Fc-Igs, Ig-based chimeric fusion proteins and Fc-tag proteins) are composed of the Fc domain of IgG genetically linked to a peptide or protein of interest. Fc fusion proteins have become valuable reagents for in vivo and in vitro research.
Examples of Fc-fused binding partners include, but are not limited to, single peptides, ligands activated upon cell-surface receptor binding, signaling molecules, extracellular domains of receptors activated upon dimerization and bait proteins used to identify binding partners in protein microarrays.
One of the most valuable characteristics conferred by the Fc domain in vivo is the dramatic prolonging of the plasma half-life (t1/2) of the protein of interest, which for biotherapeutic drugs can result in improved therapeutic efficacy, an attribute that has made Fc fusion proteins attractive biotherapeutic agents.
In vitro applications of Fc fusion proteins include, among others, immunohistochemistry (IHC), flow cytometry (FC), protein binding assays and use as microarray baits. In these applications, the Fc domain behaves as a supporting module to which proteins can be attached while retaining their native biological activity. The Fc domain can also improve the in vivo and in vitro solubility and stability of some binding partners.
Absolute Antibody offer a diverse array of recombinant Fc fusion proteins with a range of species-specific and genetically engineered Fc domains such as Fc Silent™.
For further information or for bulk and custom orders, do not hesitate to contact us.
Catalog Number | Product Name | Recombinant Protein Species | Immunoglobulin Fc domain Isotype and Species | Intro Price | Availability | Product Page |
---|---|---|---|---|---|---|
Pr00246-10.9 | Recombinant human NR3L1 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00245-10.9 | Recombinant human FCRL6 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In preparation, contact us | View Datasheet |
Pr00244-10.9 | Recombinant human BY55 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00243-10.9 | Recombinant human TIMG2 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00242-10.9 | Recombinant human TMM81 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In preparation, contact us | View Datasheet |
Pr00241-10.9 | Recombinant human NCAM1 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00240-10.9 | Recombinant human LINGO2 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00239-10.9 | Recombinant human LAIR2 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00238-10.9 | Recombinant human LAIR1 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00237-10.9 | Recombinant human HAVCR1 Fc-Fusion Protein | Human | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00236-10.9 | Recombinant human CADM1 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00235-10.9 | Recombinant human AMIGO3 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In preparation, contact us | View Datasheet |
Pr00234-10.9 | Recombinant human CD70 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00233-1.9 | Recombinant mouse 4-1BB Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00232-1.28 | Recombinant mouse TL1A Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00231-1.9 | Recombinant mouse CD155 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00230-1.9 | Recombinant mouse CD96 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00228-1.9 | Recombinant mouse TIM-3 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00227-1.9 | Recombinant mouse TIM-1 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In preparation, contact us | View Datasheet |
Pr00226-1.9 | Recombinant mouse CD86 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00225-1.9 | Recombinant mouse CD80 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00224-1.9 | Recombinant mouse BTLA Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00223-1.9 | Recombinant mouse HVEM Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In preparation, contact us | View Datasheet |
Pr00206 | Recombinant mouse CD52-Fc Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00205 | Recombinant mouse Fc-CD52 Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00188-10.9 | Recombinant human SLAF6 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00187-10.9 | Recombinant human TNR4 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00186-10.28 | Recombinant human CD69 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00185-10.9 | Recombinant human SEM4D Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00183-10.9 | Recombinant human NKG2-F Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In preparation, contact us | View Datasheet |
Pr00182-10.9 | Recombinant human TNR9 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00181-10.9 | Recombinant human CEACAM1 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00180-10.9 | Recombinant human SLAF7 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00179-10.9 | Recombinant human CD27 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00178-10.9 | Recombinant human PTPRC Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In preparation, contact us | View Datasheet |
Pr00164-1.9 | Recombinant mouse VISTA Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00163-1.9 | Recombinant mouse TIGIT Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00162-1.9 | Recombinant mouse Lag3 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00161-1.28 | Recombinant mouse CD70 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00160-1.9 | Recombinant mouse CD27 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00159-1.28 | Recombinant mouse 4-1BBL Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00158-1.9 | Recombinant mouse B7-H3 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00157-1.9 | Recombinant mouse ICOSL Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00156-1.9 | Recombinant mouse PDL2 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00155-1.9 | Recombinant mouse CTLA4 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00154-1.9 | Recombinant mouse OX40 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00153-1.9 | Recombinant mouse ICOS Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00152-1.9 | Recombinant mouse PD-1 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In preparation, contact us | View Datasheet |
Pr00136 | Recombinant human CTLA-4 Fc-Fusion Protein (Abatacept) | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00135 | Recombinant human TNFR1B Fc-Fusion Protein (Etanercept) | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00128-10.28 | Recombinant human NKG2E Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00127-10.9 | Recombinant human NCTR1 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00126-10.9 | Recombinant human NCTR3 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00125-10.28 | Recombinant human NKG2D Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00124-10.9 | Recombinant human CD96 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00123-10.9 | Recombinant human CD226 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00122-10.9 | Recombinant human TIGIT Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00117-10.9 | Recombinant human EGFR Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00113-1.9 | Recombinant mouse CD47 (C33 to G mutation) Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00112-1.9 | Recombinant mouse PDL1 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00111-1.9 | Recombinant mouse TNFR1 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00109-1.9 | Recombinant mouse IL2 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00103-10.13 | Recombinant Human CTLA-4 Fc Silent™-Fusion Protein | Human | Human IgG1 Fc Silent™ mutations in the Fc | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00103-10.9 | Recombinant Human CTLA-4 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00439 | Recombinant Human ACE2-IgG Fc (LALA)-Fusion Protein | Human | Human IgG1 (with silencing LALA mutations) | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00441 | Recombinant Human ACE2-NN-IgG Fc (LALA)-Fusion Protein | Human | Human IgG1 (with silencing LALA mutations) | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00251 | Recombinant S1-camel Fc-Fusion Protein | MERS | Camel | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | View Datasheet |
Pr00118-1.9 | Recombinant IL-13 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | |
Pr00510-1.9 | Recombinant CD40 Fc-Fusion Protein | Mouse | Mouse IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | |
Pr00511-10.9 | Recombinant CD40 Fc-Fusion Protein | Human | Human IgG1 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | |
Pr00512-201.9 | Recombinant CD40 Fc-Fusion Protein | Dog | Dog IgG2 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | |
Pr00513-201.9 | Recombinant PD1 Fc-Fusion Protein | Dog | Dog IgG2 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | |
Pr00514-201.9 | Recombinant PDL1 Fc-Fusion Protein | Dog | Dog IgG2 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | |
Pr00515-201.9 | Recombinant ICOS Fc-Fusion Protein | Dog | Dog IgG2 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock | |
Pr00516-201.9 | Recombinant CTLA4 Fc-Fusion Protein | Dog | Dog IgG2 | 0.1mg for £280 / €310 / $320 1mg for £1440 / €1640 / $1670 | In Stock |