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- Ab00385-1.1 Anti-SV40 large Tumor Antigen [405]
- SV40
- Mouse IgG1
- Purified
- In Stock
- Ab00385-1.4 Anti-SV40 large Tumor Antigen [405]
- SV40
- Mouse IgG1
- Fc Silent™
- Purified
- Ships in 4-5 weeks
Recombinant monoclonal antibody to SV40 large Tumor Antigen. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 405.
UniProt Accession Number of Target Protein: P03070
Alternative Name(s) of Target: SV40TA; Simian Virus 40 large T antigen
Immunogen: SV40 T antigen from Sf9 insect cells.
Specificity: The antibody binds specifically to the carboxy-terminus of the SV40 T antigen.
Application Notes: The antibody binds to the SV40 T antigen, a hexameric protein that acts as a proto-oncogene capable of transforming cells, for examble via inhibition of pRB or p53.
Antibody first published in:
Shearer et al. Molecular characterization of immunoglobulin variable regions from murine monoclonal antibodies specific for simian virus 40 large tumour antigen. Scandinavian Journal of Immunology 1994; 40(4)415-422 PMID:7939414
Note on publication:
Describes the generation of three monoclonal antibodies against the SC40 T-antigen.