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- Ab04004-1.1 Anti-D-Dimer [3A8]
- Human
- Mouse IgG1
- Purified
- Ships in 5-6 weeks
- Ab04004-23.0 Anti-D-Dimer [3A8]
- Human
- Rabbit IgG
- Purified
- Ships in 5-6 weeks
Recombinant monoclonal antibody to D-Dimer. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 3A8.
UniProt Accession Number of Target Protein: P02671
Alternative Name(s) of Target: XDP; Fragment D-dimer; Fibrin degradation fragment; Fibrin degradation product; Fibrin
Immunogen: The original antibody was generated by immunizing BALB/c mice with human D-dimer as an immunogen.
Specificity: This antibody binds fragment D chains of fibrinogen (Fragment D), also called D-dimer. D-dimer is a protein fragment (small piece) that's made when a blood clot dissolves in your body. At D-dimer test is done to determine if a person has any blood clotting disorder.
Application Notes: The initial binding characterization of this antibody to human D-dimer fragment was done using ELISA. DD-3A8 and DD-2E7 bind different epitope of the human D-dimer fragment and can be used as antibody pair for detection of blood coagulation, where DD-3A8 acts as a capture antibody and DD-2E7 is used as detection antibody. The sensitivity of the double sandwich ELISA was reported to be 0.25 μg/ml (CN111057149).
Antibody first published in: PMID: