United Kingdom (UK)
Recombinant monoclonal antibody to Ferritin H. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma H107.
UniProt Accession Number of Target Protein: P02794
Alternative Name(s) of Target: FTH1; FTHL6; Ferritin heavy chain; Ferritin H subunit
Immunogen: The original antibody was generated by immunizing BALB/c mice with human heart ferritin.
Specificity: This antibody binds the H subunit of human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.
Application Notes: The binding characterization of this antibody for H subunit of ferritin was done using ELISA and immunoprecipitation (PMID: 3089283).
Antibody first published in:
Luzzago et al. Immunochemical characterization of human liver and heart ferritins with monoclonal antibodies. Biochim Biophys Acta. 1986 Jul 25;872(1-2):61-71. PMID:3089283
Note on publication:
Describes the generation of 27 murine antibodies against human liver and heart ferritins.