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- Ab02600-1.1 Anti-IL-17A [3D11]
- Chicken
- Mouse IgG1
- Purified
- Ships in 5-6 weeks
- Ab02600-23.0 Anti-IL-17A [3D11]
- Chicken
- Rabbit IgG
- Purified
- Ships in 5-6 weeks
Recombinant monoclonal antibody to IL-17A. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybrodoma 3D11.
UniProt Accession Number of Target Protein: B4ER12
Alternative Name(s) of Target: Interleukin 17A; chIL-17; Interleukin-17A; IL-17; chicken IL-17A
Immunogen: The original antibody was raised by immunizing BALB/C mice with recombinant chicken IL-17.
Specificity: The antibody binds specifically to chicken IL-17, a proinflammatory cytokine produced by activated T cells. The antibody binds moderately to duck IL17.
Application Notes: The specificity of this antibody was confirmed in ELISA analysis. The antibody detected the recombinant chIL-17A by western blot on CU205 cells. The antibody was used with Con A-stimulated splenocytes in Northern blot analysis (Yoo et al, 2008; pmid: 18022248). The cross-reactivity of the antibody to chIL17 with duck IL17 was evaluated by indirect ELISA. The antibody bound moderately to duIL17 (Yoo et al., 2009; pmid: 19573930).
Antibody first published in:
Yoo et al. Monoclonal antibodies reactive with chicken interleukin‐17. Vet Immunol Immunopathol. 2008;121(3‐4):359 ‐363. PMID:18022248
Note on publication:
The article describes the generation and characterization of the antibody.