Anti-Langerin [2G3]

Description:

Recombinant monoclonal antibody to Langerin. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 2G3.

Clone Name:

2G3

Published Application(s):

FC, IHC-Fr

Published Species Reactivity:

Human

Products based on this clone:

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Please Select

Ab00642-1.1 Anti-Langerin [2G3]
Human
Mouse IgG1
Purified
In Stock

Ab00642-23.0 Anti-Langerin [2G3]
Human
Rabbit IgG
Purified
In Stock

UniProt Accession Number of Target Protein: Q9UJ71

Alternative Name(s) of Target: CD207; C-type lectin domain family 4 member K; CLC4K
Immunogen: Human Langerin ectodomain fused to human IgFc

Specificity: This antibody binds to the ectodomain of Langerin (CD207).

Application Notes: This antibody can be used to identify Langerin-positive dendritic cells. This antibody has also been used to specifically target vaccine-peptides to dendritic cells.

Antibody first published in: Igyártó et al. Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses. Immunity. 2011 Aug 26;35(2):260-72. PMID:21782478
Note on publication: Describes the generation of the antibody and use in identifying Langerin-positive cells.

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