Anti-PAR2 [1B5]

Name: Anti-PAR2 [1B5]
SKU: Ab03123
Availability: InStock

Description:

Recombinant monoclonal antibody to PAR2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 1B5.

Clone Name:

1B5

Published Application(s):

ELISA

Published Species Reactivity:

Human

Products based on this clone:

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Ab03123-23.0 Anti-PAR2 [1B5]
Human
Rabbit IgG
Purified
In Stock

Ab03123-10.0 Anti-PAR2 [1B5]
Human
Human IgG1
Purified
Ships in 4-5 weeks

Ab03123-10.3 Anti-PAR2 [1B5]
Human
Human IgG1
Fc Silent™
Purified
Ships in 4-5 weeks

Ab03123-1.1 Anti-PAR2 [1B5]
Human
Mouse IgG1
Purified
In Stock

UniProt Accession Number of Target Protein: P55085

Alternative Name(s) of Target: F2RL1; PAR-2; GPR11; Proteinase-activated receptor 2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1
Immunogen: The original antibody was generated by immunizing XenoMouse™ with PAR-2 antigen.

Specificity: This antibody binds human PAR2 or proteinase-activated receptor 2 upstream to its cleavage site. PAR2 acts as a receptor for trypsin and trypsin-like enzymes coupled to G proteins.

Application Notes: The initial screening of this antibody for reactivity for PAR2 was done using ELISA. The equilibrium dissociation constant (KD) of this antibody was obtained using KinExA® software and by “n-curve analysis” and it was reported that the original antibody had a KD of 3.39 nM with a 95% confidence interval of 1.36 to 5.47 nM (US8357367).

Antibody first published in: PMID:

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