Anti-Parvalbumin [3E1G12B6]

Name: Anti-Parvalbumin [3E1G12B6]
SKU: Ab02584
Availability: InStock

Description:

Recombinant monoclonal antibody to Parvalbumin . Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 3E1G12B6.

Clone Name:

3E1G12B6

Published Application(s):

WB, ELISA

Published Species Reactivity:

Fish

Products based on this clone:

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Ab02584-23.0 Anti-Parvalbumin [3E1G12B6]
Fish
Rabbit IgG
Purified
Ships in 5-6 weeks

Ab02584-1.1 Anti-Parvalbumin [3E1G12B6]
Fish
Mouse IgG1
Purified
In Stock

UniProt Accession Number of Target Protein: E3TEC5

Alternative Name(s) of Target: Parvalbumin; PRV7; 3E1
Immunogen: The mouse version of this antibody was raised by immunizing a mouse with heat-treated catfish sarcoplasmic protein extract.

Specificity: This antibody is specific for fish parvalbumin. Its epitope is IKKAFAVID. In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

Application Notes: Both a western blot and an ELISA were performed on fish proteins using the mouse version of this antibody to characterize the binding of this antibody (Gajewski and Hsieh, 2009; pmid:19435232). To study relationships among matrix effect, extractability, and thermostability during in vitro immunodetection, a western blot was performed on both crude fish extract and purified parvalbumin (Keshavarz et al, 2019; pmid:30372974). To analyse the immunochemical properties of pepsin digested tropomyosin peptide fragments from Atlantic salmon and flathead grey mullet, a western blot was performed on purified parvalbumin (Keshavarz et al, 2020).

Antibody first published in: Gajewski and Hsieh Monoclonal antibody specific to a major fish allergen: parvalbumin J Food Prot. 2009 Apr;72(4):818-25. PMID:19435232
Note on publication: An antibody was generated against the fish allergen parvalbumin and further characterized.

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