United Kingdom (UK)
Recombinant monoclonal antibody to SAPAP2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody SC27.
UniProt Accession Number of Target Protein: P97837
Alternative Name(s) of Target: Disks large-associated protein 2; Dlgap2; PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2;
DAP-2
Immunogen: This antibody was generated against the SAPAP2 antigen.
Specificity: This antibody is specific for SASAP2. SASAP2 may play a role in the molecular organization of synapsees and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
Application Notes: This antibody is recommended for detection and analysis of SAPAP2 by ELISA, immunofluorescence, immunohistochemistry and western blot.
Antibody first published in:
Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360
Note on publication:
Describes the generation of a library of recombinant monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for neuroscience research.