United Kingdom (UK)
Recombinant monoclonal antibody to Serum Albumin. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 3B8-H3-G1.
Alternative Name(s) of Target: HSA-1; Albumin; ALB
Immunogen: The mouse version of this antibody was raised by immunizing a BALB/c mouse with human serum albumin.
Specificity: This antibody is specific for human serum albumin. Albumin binds water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood.
Application Notes: To create an assay which can measure albumin, an ELISA was performed on human albumin using the mouse version of this antibody (Benjamin et al, 1987; pmid:2437011).
Antibody first published in:
Benjamin et al. A unique epitope on human serum albumin recognized by monoclonal antibody HSA-1: a probe for identification of the human origin of blood or tissue Hybridoma. 1987 Apr;6(2):183-90. PMID:2437011
Note on publication:
A double antibody ELISA assay was developed using biotinylated HSA-1 as the specific probe for human albumin. This assay was capable of detecting as little as 30 nanograms or less albumin/ml. This assay was used to verify the presence of human albumin in blood, tissue extracts, and other body fluids.