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- Ab03967-23.0 Anti-anti-BSW17 [Clone 52]
- Human
- Rabbit IgG
- Purified
- Ships in 5-6 weeks
Recombinant monoclonal antibody to anti-BSW17. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody Clone 52.
Alternative Name(s) of Target: BSW17 mimetic antibody; anti-idiotype-BSW17
Immunogen: The original antibody was isolated from a human antibody library by panning against BSW17.
Specificity: The antibody specifically binds to BSW17.
Application Notes: The specificity of the antibody for BSW17 was determined by ELISA analysis. The antibody was able to induce the production of anti-mimic antibodies in vivo. After the second booster immunization of the antibody preparation, all mice produced antibodies against the mock antibody. The binding affinity of the antibody to IgE was measured by surface plasmon resonance (Kd= 5.0±2.2 nM for Myeloma IgE and Kd= 6.0±1.8 nM for SUS-11IgE). Vaccination of rhesus monkeys by the antibody could inhibit passive skin allergy reaction (CN1268644C).
Antibody first published in: PMID: