Anti-paclitaxel [1C2]

Name: Anti-paclitaxel [1C2]
SKU: Ab01156
Availability: InStock

Description:

Recombinant monoclonal antibody to paclitaxel. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 1C2.

Clone Name:

1C2

Published Application(s):

ELISA

Published Species Reactivity:

Products based on this clone:

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Ab01156-1.1 Anti-paclitaxel [1C2]
Mouse IgG1
Purified
In Stock

Ab01156-23.0 Anti-paclitaxel [1C2]
Rabbit IgG
Purified
In Stock

Alternative Name(s) of Target: PT; PTX; Taxol; 7-Xylosylpaclitaxel; Taxol-7-xyloside; 7-xylosyltaxol
Immunogen: This antibody was raised by immunising BALB/c mice with a solution of 7-xylosyltaxol conjugated to the carrier protein bovine serum albumin (XylTax–BSA).7-xylosyltaxol is a taxol (paclitaxel) derivative, which binds to tubulin and inhibits microtubule dis

Specificity: This antibody is specific for paclitaxel, an anti-neoplastic agent derived from the Pacific yew.

Application Notes: The reactivity of this antibody for free and immobilised paclitaxel has been confirmed in ELISA analysis (Yusakul et al, 2018).

Antibody first published in: Yusakul et al. Different expression systems resulted in varied binding properties of anti‑paclitaxel single‑chain variable fragment antibody clone 1C2 J Nat Med (2018) 72:310–316 PMID:29027080
Note on publication: Describes the original generation of this antibody, and the derivation of an scFv with the same binding specificity.

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