Anti-Alpha-Fetoprotein [AFP01]

Description:

Recombinant monoclonal antibody to Alpha-Fetoprotein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma AFP01.

Clone Name:

AFP01

Published Application(s):

ELISA, IF

Published Species Reactivity:

Human

Products based on this clone:

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Ab03492-23.0 Anti-Alpha-Fetoprotein [AFP01]
Human
Rabbit IgG
Purified
Ships in 5-6 weeks

Ab03492-1.1 Anti-Alpha-Fetoprotein [AFP01]
Human
Mouse IgG1
Purified
Ships in 5-6 weeks

Ab03492-21.0 Anti-Alpha-Fetoprotein [AFP01]
Human
Mouse IgM
Purified
Ships in 5-6 weeks

UniProt Accession Number of Target Protein: P02771

Alternative Name(s) of Target: AFP; Alpha-fetoglobulin; A-Feto-protein
Immunogen: The original antibody was generated by immunizing healthy 6-8 week old BALB/c mice with human alpha-fetoprotein.

Specificity: This antibody binds human alpha-fetoprotein (AFP). AFP is made in the liver of developing babies. It binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. AFP levels in healthy adults is very low. Elevated levels of AFP in adult human blood is a marker for cancer.

Application Notes: This antibody is capable of binding human alpha-fetoprotein and can recognize human HepG2 hepatoma cells in an immunofluorescence staining. The additional binding characterization of this antibody for human alpha fetoprotein was done using ELISA. This antibody has a wide detection range, high sensitivity with detecting concentration of hAFP in the range of 2 ~ 400ng / mL, the detection limit is 2ng / mL. (CN108484762).

Antibody first published in: PMID:

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