Anti-Capsid protein VP1 [Mab6]

Name: Anti-Capsid protein VP1 [Mab6]
SKU: Ab04383
Availability: InStock

Description:

Recombinant monoclonal antibody to Capsid protein VP1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma Mab6.

Clone Name:

Mab6

Published Application(s):

cryoEM, neutralizing, ELISA

Published Species Reactivity:

Canine parvovirustype 2, feline panleukopenia virus

Products based on this clone:

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Ab04383-23.0 Anti-Capsid protein VP1 [Mab6]
Canine parvovirustype 2, feline panleukopenia virus
Rabbit IgG
Purified
Ships in 5-6 weeks

Ab04383-2.3 Anti-Capsid protein VP1 [Mab6]
Canine parvovirustype 2, feline panleukopenia virus
Mouse IgG2a
Fc Silent™
Purified
Ships in 5-6 weeks

Ab04383-2.0 Anti-Capsid protein VP1 [Mab6]
Canine parvovirustype 2, feline panleukopenia virus
Mouse IgG2a
Purified
Ships in 5-6 weeks

UniProt Accession Number of Target Protein: P17455; P04864

Alternative Name(s) of Target: CPV; FPV; Fab 6; Coat protein VP1; Antibody 6
Immunogen: The original antibody was generated by immunizing Balb/C mice with CPV antigen.

Specificity: The antibody is specific for CPV and FPV. The antibody is specific for antigenic site A of CPV-2.

Application Notes: The original format of the antibody could neutralize CPV and FPV (Parrish et al., 1982; PMID: 6180709 and Nelson et al., 2007; PMID: 17217977). The specificity of the original format of the antibody was confirmed by ELISA analysis (Nelson et al., 2007; PMID: 17217977). The crystal structure of the Fab format of the antibody was determined by cry-electron microscopy (Hafenstein et al., 2009; PMID: 19321620).

Antibody first published in: Parrish et al. Antigenic relationships between canine parvovirus type 2, feline panleukopenia virus and mink enteritis virus using conventional antisera and monoclonal antibodies Arch Virol. 1982;72(4):267-78. doi: 10.1007/BF01315223. PMID:6180709
Note on publication: The original paper describes the generation and characterization of the antibody.

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