- Ab00223-3.0 Anti-CCR3 (CD193) [5E8-G9-B4]
- Mouse IgG2b
- In Stock
- Ab00223-23.0 Anti-CCR3 (CD193) [5E8-G9-B4]
- Rabbit IgG
- In Stock
Recombinant monoclonal antibody to CCR3 (CD193). Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 5E8-G9-B4.
UniProt Accession Number of Target Protein: P51677
Alternative Name(s) of Target: C-C Motif Chemokine Receptor 3
Specificity: Recognises human CCR3, a chemokine receptor highly expressed of eosinophils, as well as Th2-Tcells, basophils, platelets, mast-cells, mononuclear phagocytes, airway epithelial cells, and hematopoietic progenitor cells (CD34+).
Antibody first published in: Heath et al. Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody. J Clin Invest. 1997 Jan 15;99(2):178-84. PMID:9005985
Flow-cytometry using anti-CCR3 antibody 5 E8-G9-B4 (Ab00223) Human leukocytes were stained with an isotype control (Ab00102-23.0, panel A) or the rabbit-chimeric version of 5 E8-G9-B4 (Ab00223-23.0, panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody (ab150073) and cells analysed on a FACSCanto flow-cytometer.