Anti-CD14 [28C5]

Name: Anti-CD14 [28C5]
SKU: Ab01483
Availability: InStock

Description:

Recombinant monoclonal antibody to CD14. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 28C5.

Clone Name:

28C5

Published Application(s):

Blocking

Published Species Reactivity:

Human

Products based on this clone:

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Ab01483-1.1 Anti-CD14 [28C5]
Human
Mouse IgG1
Purified
Ships in 4-5 weeks

Ab01483-23.0 Anti-CD14 [28C5]
Human
Rabbit IgG
Purified
Ships in 4-5 weeks

Ab01483-10.0 Anti-CD14 [28C5]
Human
Human IgG1
Purified
Ships in 4-5 weeks

Ab01483-10.3 Anti-CD14 [28C5]
Human
Human IgG1
Fc Silent™
Purified
Ships in 4-5 weeks

Ab01483-13.12 Anti-CD14 [28C5]
Human
Human IgG4-S228P
Purified
Ships in 4-5 weeks

UniProt Accession Number of Target Protein: P08571

Alternative Name(s) of Target: Monocyte antigen; Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein
Immunogen: This antibody was raised by immunising mice with full length human recombinant polypeptide for soluble CD14.

Specificity: This antibody recognises CD14, which is expressed strongly by macrophages and most tissue monocytes. Native CD14 also is spontaneously released from the surface of mature monocytes and macrophages in a soluble form.

Application Notes: This antibody is recommended for the detection of the presence of cell surface and soluble CD14 in a sample. Furthermore, it might be used in the research and development the methods to treat and prevent disorders with CD14 mediated cell activation, such as sepsis.

Antibody first published in: Leturcq et al. HYBRID CELLS PRODUCING MONOCLONAL ANTI-CD14 ANTIBODIES U.S. Patent 7,326,569 PMID:
Note on publication: This patent describes the generation and use of 28C5 blocking antibody.