- {{heading}}
- Ab03295-23.0 Anti-CD19 [26D3]
- Human
- Rabbit IgG
- Purified
- Ships in 4-5 weeks
- Ab03295-1.1 Anti-CD19 [26D3]
- Human
- Mouse IgG1
- Purified
- Ships in 4-5 weeks
Recombinant monoclonal antibody to CD19. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 26D3.
UniProt Accession Number of Target Protein: P15391
Alternative Name(s) of Target: B4 antigen; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; LE-CD19
Immunogen: The original antibody was generated by immunizing mice with CD19.
Specificity: The antibody is specific for CD19. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens.
Application Notes: The antibody detected the recombinant CD19 by western blot analysis. The antibody was used to stain and analyze prostate tissue, B-cell lymphoma samples and tonsil B lymphocytes by immunohistochemistry. Further, immunohistochemistry staining from 26D3 antibody and the commercial antibody, LE-CD19, were compared. Results showed that the specificity of the 26D3 antibody in tumor tissue was equivalent to the commercial antibody, while sensitive and affinity were higher than the commercial antibody (CN103880960).
Antibody first published in: PMID: