Anti-CEACAM5 [NbCEA5]

Description:

Recombinant monoclonal antibody to CEACAM5. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody NbCEA5.

Clone Name:

NbCEA5

Published Application(s):

FACS, SPR, ELISA

Published Species Reactivity:

Human

UniProt Accession Number of Target Protein: P06731

Alternative Name(s) of Target: CEA; CD66e; CEA#1; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; Meconium antigen 100

Specificity: This antibody is specific for human CEACAM5

Application Notes: The binding of the original version of this antibody (VHH) to CEACAM5 was characterized in an SPR (K_D 0.41 nM), ELISA (EC₅₀ of 0.026 nM), and FACS (EC₅₀ of 1.0 nM). In its bi-specific construction with Ab04389 (Anti-EGFR [7D12]), it served as an anchor (US20220242958).

Antibody first published in: PMID: Note on publication: The original publication describes the construction and characterization of various bi-specific antibodies.

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