United Kingdom (UK)
Recombinant monoclonal antibody to CMV coat protein. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody 6A1.
Alternative Name(s) of Target: CMV; Cucumber mosaic virus; CM2
Immunogen: The original antibody was isolated from an scFv phage display antibody library generated from variable genes (V gene) from the hybridoma cells CM2 and panning the library against CMV.
Specificity: This antibody binds the coat protein or the capsid protein of the Cucumber mosaic virus (CMV).
Application Notes: This antibody was derived from the parent antibody called CM2, after PCR cloning the variable region genes of the hybridoma to generate a phage display library and isolating the specific clone that showed reactivity towards CMV. The binding specificity of this antibody for CMV was determined using ELISA. The scFv antibody was also able to identify CMV coat protein in a western blot assay (Koohapitagtam et al., 2009).
Antibody first published in:
Koohapitagtam et al. Construction of Single-Chain Variable Fragment (scFv) Specific to Cucumber Mosaic Virus by Phage Display Technology. Kasetsart J. (Nat. Sci.) 2009; 43 : 330 - 338 . PMID:
Note on publication:
Describes the generation and characterization of this recombinant phage display antibody clone.