- {{heading}}
- Ab03692-23.0 Anti-F [ACN044]
- human metapneumovirus
- Rabbit IgG
- Purified
- In Stock
Recombinant monoclonal antibody to F. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody ACN044.
UniProt Accession Number of Target Protein: Q6WB98
Alternative Name(s) of Target: hMPV; Fusion glycoprotein F0; Protein F
Immunogen: Phage antibody libraries were prepared from human donor tissues. The original antibody was selected against recombinant hMPV F protein with multiple rounds of panning.
Specificity: The antibody is specific for HMPV lineage A2.
Application Notes: The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody could specifically bind to hMPV-infected cell monolayers as shown by immunofluorescent assays. The Fab fragment exhibited in vitro neutralizing activity (1.3 ug/mL) (Williams et al. 2007; PMID:17522220).
Antibody first published in:
Williams et al. A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo J Virol. 2007 Aug;81(15):8315-24. PMID:17522220
Note on publication:
The original paper describes the generation and characterization of the antibody.