- Ab00231-5.0 Anti-Ganglioside GD3 [R24]
- Mouse IgG3
- Ships in 4-5 weeks
- Ab00231-23.0 Anti-Ganglioside GD3 [R24]
- Rabbit IgG
- In Stock
Recombinant monoclonal antibody to Ganglioside GD3. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma R24.
Alternative Name(s) of Target: d18:1/20:0
Immunogen: SK-MEL-28 Melanoma cell line.
Specificity: Recognises GD3, a prominent ganglioside of human melanoma, melanocytes and other cells of neuroectodermal origin. It furthermore recognises strocytes, certain groups of neurons in the brain, cells in the parotid, adrenal medulla and pancreatic islets.
Antibody first published in: Kaminski et al. The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains. J Biol Chem. 1999 Feb 26;274(9):5597-604. PMID:10026176