Anti-Glypican-1 [AbAb-GPC1]

Description:

Recombinant monoclonal antibody to Glypican-1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the rabbit peripheral blood lymphocytes AbAb-GPC1.

Clone Name:

AbAb-GPC1

Published Application(s):

ELISA, FC

Published Species Reactivity:

Human

Products based on this clone:

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Ab03427-23.0 Anti-Glypican-1 [AbAb-GPC1]
Human
Rabbit IgG
Purified
In Stock

Ab03427-10.0 Anti-Glypican-1 [AbAb-GPC1]
Human
Human IgG1
Purified
Ships in 5-6 weeks

Ab03427-10.3 Anti-Glypican-1 [AbAb-GPC1]
Human
Human IgG1
Fc Silent™
Purified
Ships in 5-6 weeks

UniProt Accession Number of Target Protein: P35052

Alternative Name(s) of Target: GPC1
Immunogen: The original antibody was generated by immunizing 6-week-old healthy New Zealand female white rabbits subcutaneously with human glypican-1.

Specificity: This antibody binds human glypican-1, which is a cell surface proteoglycan that bears heparan sulfate. This protein is required for skeletal muscle differentiation. Glypican-1 (GPC1) was significantly expressed in serum exosomes of patients with pancreatic cancer and so GPC1 is considered as a tumor marker for pancreatic cancer.

Application Notes: The binding characterization of this antibody to human glypican-1 was determined using ELISA. The binding of this antibody to human glypican-1 expressed on the surface of human breast cancer cell line MDA-MB-231 was determined using flow cytometry (CN112300283).

Antibody first published in: PMID:

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