- Ab00633-10.0 Anti-IFN gamma [A4]
- Human IgG1
- In Stock
- Ab00633-10.6 Anti-IFN gamma [A4]
- Human Fab fragment
- Ships in 4-5 weeks
- Ab00633-23.0 Anti-IFN gamma [A4]
- Rabbit IgG
- In Stock
Recombinant monoclonal antibody to IFN gamma. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the phage display antibody A4.
UniProt Accession Number of Target Protein: P01579
Alternative Name(s) of Target: IFNG; Interferon gamma; Immune interferon ; IFN-gamma
Immunogen: 2D-PAGE gel isolated human IFN gamma from lysate of human melanoma COLO-38 cells.
Specificity: This antibody binds to human Interferon gamma
Application Notes: The antibody binds specifically to IFN gamma, a dimerised soluble cytokine member of the type II class of interferons synthesised by activated T-lymphocytes and natural killer (NK) cells. . IFNγ plays a role in both the innate and adaptive immune responses, and is important in the activation of macrophages, induces the expression of MHC class I molecules, and has antiviral and immunoregulatory activities.
Antibody first published in:
Pini et al. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J Biol Chem. 1998 Aug 21;273(34):21769-76. PMID:9705314
Note on publication: Describes generation, using phage display, of antibodies with subnanomolar affinity against markers of angiogenesis.