United Kingdom (UK)
Recombinant monoclonal antibody to IGF-1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 7973 [M23].
UniProt Accession Number of Target Protein: P08069
Alternative Name(s) of Target: CD221; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor
Immunogen: The original antibody was raised by immunizing a mouse with IGF-1.
Specificity: This antibody is specific for IGF-1.
Application Notes: The original version of this antibody was used for immunohistochemistry on infraorbital nerve tissue. The antibody was able to stain the IGF-1 protein in the tissue (Sugawara et al., 2019; PMID: 31861182). This antibody was used for a western blot on injured or sham-treated infraorbital nerve and trigeminal ganglion (Sugawara et al., 2019; PMID: 31861182), on PC-12 cells (Wang et al., 2021; PMID: 33484421), and on hUCMSCs (Li et al., 2017; PMID: 28279229).
Antibody first published in:
Li et al. Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism Stem Cell Res Ther. 2017 Mar 9;8(1):55. PMID:28279229
Note on publication:
The original paper designs an experimental study in order to investigate whether the transplantation of hUCMSCs can improve the ovarian reserve function of perimenopausal rats and delay ovarian senescence.