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- Ab02594-1.1 Anti-IL-2 [16]
- Chicken
- Mouse IgG1
- Purified
- Ships in 5-6 weeks
- Ab02594-23.0 Anti-IL-2 [16]
- Chicken
- Rabbit IgG
- Purified
- Ships in 5-6 weeks
Recombinant monoclonal antibody to IL-2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 16.
UniProt Accession Number of Target Protein: O73883
Alternative Name(s) of Target: Interleukin 2; ChIL-2/16; Interleukin
Immunogen: The original antibody was raised by immunising BALB/c mice with recombinant chicken IL-2.
Specificity: The antibody binds specifically to chicken IL-2, a type of cytokine signaling molecule in the immune system. The antibody did not react with chicken IFN-gamma or chicken IL-15.
Application Notes: The specificity of this antibody (IgG1) was confirmed in ELISA analysis. The antibody detected the recombinant chIL-2 by western blot. The antibody showed neutralizing chIL-2 activity in NK cell assay. The antibody was used as a capture antibody in capture ELISA (Miyamoto et al, 2001; pmid: 11457478).
Antibody first published in:
Miyamoto et al. Production and characterization of monoclonal antibodies detecting chicken interleukin‐2 and the development of an antigen capture enzyme‐linked immunosorbent assay Vet Immunol Immunopathol. 2001;80(3‐4):245‐257. PMID:11457478
Note on publication:
The article describes the generation of the antibody, and its use in investigating the functionality of chicken IL-2.