- Ab00642-1.1 Anti-Langerin [2G3]
- Mouse IgG1
- In Stock
- Ab00642-23.0 Anti-Langerin [2G3]
- Rabbit IgG
- In Stock
Recombinant monoclonal antibody to Langerin. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 2G3.
UniProt Accession Number of Target Protein: Q9UJ71
Alternative Name(s) of Target: CD207; C-type lectin domain family 4 member K; CLC4K
Immunogen: Human Langerin ectodomain fused to human IgFc
Specificity: This antibody binds to the ectodomain of Langerin (CD207).
Application Notes: This antibody can be used to identify Langerin-positive dendritic cells. This antibody has also been used to specifically target vaccine-peptides to dendritic cells.
Antibody first published in:
Igyártó et al. Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses. Immunity. 2011 Aug 26;35(2):260-72. PMID:21782478
Note on publication: Describes the generation of the antibody and use in identifying Langerin-positive cells.