Anti-Nkp46 [29A1.4]

Name: Anti-Nkp46 [29A1.4]
SKU: Ab04104
Availability: InStock

Description:

Recombinant monoclonal antibody to Nkp46. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 29A1.4.

Clone Name:

29A1.4

Published Application(s):

activation, FC

Published Species Reactivity:

Mouse

Products based on this clone:

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Please Select

Ab04104-23.0 Anti-Nkp46 [29A1.4]
Mouse
Rabbit IgG
Purified
In Stock

Ab04104-2.0 Anti-Nkp46 [29A1.4]
Mouse
Mouse IgG2a
Purified
In Stock

Ab04104-2.3 Anti-Nkp46 [29A1.4]
Mouse
Mouse IgG2a
Fc Silent™
Purified
Ships in 5-6 weeks

UniProt Accession Number of Target Protein: Q8C567

Alternative Name(s) of Target: CD335; NK-p46; NKp46; mNKp46; mAR-1; Activating receptor 1; Lymphocyte antigen 94; Natural killer cell p46-related protein; Natural cytotoxicity triggering receptor 1
Immunogen: The original antibody was generated by immunizing rats with mouse NKp46-Fc recombinant protein.

Specificity: This antibody is specific for mouse NKp46-Fc.

Application Notes: The original format of this antibody was used in an FC analysis to detect NKp46 expression on NK cells and to activate NK in an NK cell stimulation assay (Walzer et al., 2007; PMID: 17360655). This antibody was used as a component of bispecific NKCEs (Natural Killer Cell Engagers) to redirect the cytotoxic activity of NK cells towards human CD20-expressing tumor cells in a transplantable xenogeneic in vivo solid tumor model (Gauthier et al., 2019; PMID: 31155232).

Antibody first published in: PMID:

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