- Ab00938-1.1 Anti-R45-45-11 [mAb 114]
- Mouse IgG1
- Ships in 4-5 weeks
- Ab00938-23.0 Anti-R45-45-11 [mAb 114]
- Rabbit IgG
- In Stock
Recombinant monoclonal antibody to R45-45-11. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma mAb 114.
Alternative Name(s) of Target: anti-cyclosporin AbID; anti-cyclosporin antibody idiotype
Immunogen: This antibody was raised by immunising C56BL/6 mice with BALB/c-derived R45-45-11, an anti-cyclosporine monoclonal antibody.
Specificity: This anti-idiotypic antibody is recognises R45-45-11, an anti-cyclosporine mAb. It crossreacts with mAb V45-271-10.
Application Notes: In a competition ELISA, this antibody has been shown to inhibit the interaction between R45-45-11, the idiotype, and its antigen, cyclosporine (Zenke et al, 1992).
Antibody first published in:
Zenke et al. Anti-cyclosporine monoclonal antibodies and their anti-idiotopic counterpart: structure and biological activity. Mol Immunol. 1992 Mar;29(3):343-51. PMID:1557045
Note on publication: Describes the original generation of this antibody, and its characterisation in immunohistochemical and ELISA analysis.