Anti-Rhesus IgG4 [7A8]

Name: Anti-Rhesus IgG4 [7A8]
SKU: Ab01625
Availability: InStock

Description:

Recombinant monoclonal antibody to Rhesus IgG4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 7A8.

Clone Name:

7A8

Published Application(s):

ELISA

Published Species Reactivity:

Rhesus

Products based on this clone:

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Ab01625-1.1 Anti-Rhesus IgG4 [7A8]
Rhesus
Mouse IgG1
Purified
In Stock

Ab01625-23.0 Anti-Rhesus IgG4 [7A8]
Rhesus
Rabbit IgG
Purified
In Stock

Alternative Name(s) of Target: rhesus immunoglobulin G4; immunoglobulin G 4; immunoglobulin; Mumu_a_Mamu_IgG4_7A8
Immunogen: This antibody was raised by immunizing mice against a rhesus immunoglobulin.

Specificity: This antibody is specific to rhesus IgG4.

Application Notes: This antibody is recommended for the detection and analysis of rhesus IgG4. It was shown to react specifically with rhesus IgG4 via ELISA. The specificity of this antibody was further confirmed when it was used in research on CD4 follicular helper T cell skewing on antibody responses to an HIV-1 vaccine in rhesus macaques (Verma et al., 2020; pmid: 31827000).

Antibody first published in: Verma et al. Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques. J Virol. 2020 Feb 28;94(6). pii: e01737-19. doi: 10.1128/JVI.01737-19. Print 2020 Feb 28 PMID:31827000
Note on publication: This article describes the earliest published application of this antibody and confirms its specificity.

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