- {{heading}}
- Ab00413-23.0 Anti-Taq-Polymerase [TP7]
- T. aquaticus
- Rabbit IgG
- Purified
- In Stock
- Ab00413-1.1 Anti-Taq-Polymerase [TP7]
- T. aquaticus
- Mouse IgG1
- Purified
- In Stock
Recombinant monoclonal antibody to Taq-Polymerase. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma TP7.
UniProt Accession Number of Target Protein: P19821
Alternative Name(s) of Target: Taq DNA Pol; Thermostable DNA-Polymerase I
Immunogen: Taq-Polymerase.
Specificity: This antibody binds to Taq-Polymerase with a Kd of 1 nM.
Application Notes: This antibody binds to Taq-polymerase, a thermostable DNA polymerase from a therophilic bacterium frequently used in PCR as its optimum temperature is about 75-80°C and is still active at temperatures up to 92.5°C. The antibody competes with DNA for Taq-binding.
Antibody first published in:
Murali et al. Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition. Protein Engineering 1998; 11(2):79-86 PMID:9605541
Note on publication:
Describes the crystallisation of Taq-Polymerase with TP7 to identify the mechanism of inhibition and surface contacts.