United Kingdom (UK)
Recombinant monoclonal antibody to ULBP3. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 4A10.
UniProt Accession Number of Target Protein: Q9BZM4
Alternative Name(s) of Target: NKG2DL3; UL16-binding protein 3; ALCAN-gamma; N2DL-3; Retinoic acid early transcript 1N; NKG2D ligand 3; ULBP-3
Immunogen: This antibodhy was raised against human ULBP.
Specificity: This antibody recognizes human ULBP3 which binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Application Notes: This antibody is recommnended for the detection and analysis of human ULBP3. It has been successfully used in the identification of ULBP3 in flow cytometry and dot blots.
Antibody first published in:
Vankayalapati et al. Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium J Immunol. 2005 Oct 1;175(7):4611-7. doi: 10.4049/jimmunol.175.7.4611. PMID:16177106
Note on publication:
This paper describes the use of the anti-ULBP3 antibody.