Prometheus™: A novel approach for engineering manufacturable humanized antibodies

At Absolute Antibody, our Prometheus™ humanization service was developed specifically to deliver antibodies with increased manufacturability.

Download our research poster using the form below to learn more about the development of our humanization approach, which was informed by analyzing manufacturability data for more than 100 therapeutic antibodies to identify preferential manufacturing properties.

The poster also describes an antibody humanization case study, in which we created 25 different humanized variants with increased titers compared to the original chimeric antibody. The three winning candidates displayed no detectable aggregation, an approximately two-fold increase in activity, and a minimum 16-fold increase in titer compared to the chimeric antibody.

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